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lizziemouse
#61 Posted : Monday, December 28, 2009 11:51:24 AM Quote
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Does anyone know of any research into links between acute stress / RA?
This is my RA story.... please be warned its sad, i do apologise but these events in my life happened some time ago now...

In 1997, my mum went missing - she had suffered from very severe depression all her life and had attempted to take her own life several times during our childhood. Mum had been so so well in her later years, my twin sister and I saw her all the time but just before she died she had been worried about growing older and about some minor health issues.... but after several years of good health and happy times her disappearance came completely out of the blue and was traumatic beyond words.....
We always felt responsible for mums health and well being - she was a lovely lovely person with a very vulnerable soul. She left her house one October evening, got the bus to Gloucester.... then no sign...until her body was found over a week later in Gloucester docks.
Mum was missing for about 9 days. We searched for her day and night - i even went to the docks and searched there with my brother in law....as when she was really poorly years previously she had said taht was where she would go..........
During those 9 days my first symptoms appeared..... i used to read to my girls every night and they would always wear my jeweleery during the story. I realised ALL my fingers were swollen when i couldnt get any one of my rings off... I didnt make a big thing wanting to keep things as normal as possible for the girls and with mumn missing.. too many other things to think about....sophie missing her so much, jess not understanding much at all - they were so young... and me not able to explain - they were so used to seeing her all the time.......
...then after the funeral i couldnt get out of bed and i realised something was physically wrong, so so tired and in so much pain but masked by grief..... It took about a year to be diagnosed but i had alrerady diagnosed myself that first month using my sisters nursing books....
I just wonder if any research has been done into - say for example, mass production of cortisol or stress hormones? I ALWAYS urge my friends and family to look after themselves - stress is a terrible thing... in my expereince i DEFINITELY believe it triggered RA.
I cope by being positive - worse things happen physically, worse diseases, and i count my blessings, i have my lovely family, my twin sister, lots of friends and our lovely dogs...and more... and now The forum!:)
i can talk about my mum much more now and have photos up at home & try remember the good times - there were LOTS of them. My sister coped better than me, i'm sure for several years i blamed my mum sub consciously for my RA symptoms... a family suicide is so scary... so many different emotions - unbeliebvable to cope with...
I absolutely threw myself into work after mum died... gaining promotion not long after diagnosis... previously i had worked just one night a week.... i know i am stubborn by nature and have a "that wont stop me" attitude but under the circumstances, i think this helped me... but then we're all very different and i am a taurean!
im lucky with work i was able to work around paul and his shifts so one of us was almost always there with the girls...
i feel such empathy with people who are newly diagnosed it brings those feelings back i have never felt so alone than that first year before diagnosis...
i have found this forum AMAZING - i wish i had found it years before - thank u to ALL of you - you are all so helpful especially when u make me laugh out loud xxx

so, just to finish - if anyone knows of any research please let me know or maybe if there isnt any.... perhaps some research should be considered....?
Thanks for reading, take care all of you and as soon as you recognise any stress symptoms - do something asap to de-stress xxx love Liz xx
dorat
#62 Posted : Monday, December 28, 2009 12:11:16 PM Quote
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hi Lizzie,
That is so sad about your Mum, what a dreadful time for you.
We have discussed this before and almost every one of us had a period of deep stress, trauma or illness just before the first signs of RA appeared.
I seem to think there has been some research on this quite recently , also someone composed a survey which some of us filled in.

If you look back on the old forum yo may find some threads about stress and RA.

Doreen xx
Calmwater22
#63 Posted : Monday, December 28, 2009 5:13:06 PM Quote
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Smile Hi lizzie
Thankyou for sharing your life,it is sad and i can see why at that point RA decided to arrive.
Yes all my illnesses have arrived after major stress in my life/family life or work situation of great stress.
not always straight away.
Ra wise yes after starting work and finding my self caring for dying elderley clients along with own family troubles.
i dont know of any research but am aware that consultants are more aware as ive found them asking how i feel emntally not had this asked before good i feel.
my recent lupus/came about after my brother went missing for 7 days this summer and 4 days last summer.
spending much time with his wife trying to find hi being there for my parents.
caring for my huby through major surgery dealing with family disagreements oh the list rathe endless.


like u im fighting back with postive thoughts find it really helps and rest not push push push.
take care hun lv melly
cuddly cats make my world seem so much more fun
Blue Star
#64 Posted : Monday, December 28, 2009 6:02:09 PM Quote
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Hi Lizzie, sorry about your mum thats so sad, stress has definitely got some thing to do with it, i just wish doctors could come up with medicine that woud trigger the immune system back to normal x
hen
#65 Posted : Monday, December 28, 2009 7:35:11 PM Quote
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Hi Lizzie,

thankyou for sharing your RA story. It is very sad about your mum..I can only begin to imagine how dreadful that must have been for you.
I totally agree about the relevance of stress.
Are you and your twin sister identical?....I am interested in the genetics of RA.

Diane x
MrsWoman
#66 Posted : Monday, December 28, 2009 8:52:09 PM Quote
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I think it seems that stress is a common denominator for most of us. Some of us have gone through harrowing times. I am sorry to hear what you have experienced. I went through a prolonged peirod of stress we are talking years of being in a pressurised job working 12/14hrs a day that i hated, then when i left i went into a similar job which i didnt want to do but took it as I had no choice then i got mugged on my first day of work, i had a lot of family and personal stuff on top and i feel like when i got depressed py and lost a quarter of my body weight for worry when I couldnt get a job.

I am so aware of the stress effecting hormones etc but find it hard to deal with stress. Its so hard to break bad habits. I think if I can learn to look at things differently and not get so anxious then it will help to reign in my RA, but is this like shuting the stable door after the horse has left....

I have read that RA is triggered by a traumatic event, and that RA appears usually 6 months of a physical trauma. I got RA within 6 months of the mugging - and during those 6 months I was pretty stressed about finding work so i think my body couldnt take any more.

How does everyone handle stress now?


amanda_lewin
#67 Posted : Monday, December 28, 2009 10:36:25 PM Quote
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Dear Lizzie,

I am SO sorry and sad to hear of this great suffering. Only as a Mother myself can I even contemplate what an effect this must have had on you, and must still have.

You have been immensely courageous and brave. I do believe very strongly that RA can be triggered by a traumatic experience.

When I was very first dx at the age of nearly 9, I had a traumatic fall and two days later both knees swelled. But I have also had (in later years) two very large experiences of extreme stress and anguish, both physcial and emotional, and both those times my RA flared severely, taking me on the a next stage of the illness. (I may e/mail you privately regarding this, one of the times is very difficult to talk about.)

For yourself your experience follows a clear pattern which in itself shows the development of rheumatoid.

Thank God for our families , children and dear friends!

Much love and prayers,
Amanda
lizziemouse
#68 Posted : Tuesday, December 29, 2009 9:46:20 AM Quote
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Thank you ALL for your replies - it means a lot to me. Like others, I find Christmas a particularly emotional time of year and with shorter days, darker nights i think there seems more time for deep contemplative thoughts.....
Amanda (and others...) ~ you can email me any time - my email is lizziemouse@btinternet.com
Diane ~ my sister and I are non identical and like you i'm very interested in genetics - we would both be up for RA research if anyone needs non identical twins to participate!
Doreen ~ i think i took part in a survey a couple of years ago which i accessed via the nras pages i think it very lightly touched on stress - and ive had a very quick look on nras pages and it looks as if there's definitely a need for more research into links between loss of sleep (symptom of stress) and RA.
While i was doing open uni nutrition course recently, I found out that vitamin C definitely lowers the levels of cortisol in your body which is useful to know - i find it quite helpful to picture my daily fruit juice zapping my stress levels.

Thank you again to all of you ~ love Liz xx
dorat
#69 Posted : Tuesday, December 29, 2009 10:36:49 AM Quote
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lizziemouse
#70 Posted : Tuesday, December 29, 2009 11:13:47 AM Quote
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thanks Doreen - that wass really interesting....
in my case Jess was about 1 years old when symptoms first appeared so i read about other people's thoughts about hormone links with interest,
also lots of stress during our childhood although i think you just accept these things as normal when young
...at 17 i had a VERY severe case of mumps - i swelled up so much i looked like a baby elephant.
Looking back can see RA potential triggers / signs several times before diagnosis and during childhood....
Jess is double jointed with "clicky fingers" that worries me sometimes...
Like others i worry a lot about possible genetic link which i now see from those posts this is not established, i do think there may be genetic "pre-dispositions" if that makes sense....
Two of Paul's aunties have RA - each on separate sides of the family, one of those aunties has a daughter now diagnosed with Crohns disease.....
...while one of jessie's friends' mum has crohn's disease while the mum's dad has RA.....

Thank goodness for the forum so we can share worries often not just about ourselves but about our family worries too xx
Blue Star
#71 Posted : Tuesday, December 29, 2009 11:21:50 AM Quote
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That's interesting Lizzie, my mums sister has Crohn's her son has spondylosis of the spine, my mums brothers son had juvenile arthritis but has since grown out of it, my mum has osteoarthritis and is allergic to pain killers and lots of other things and i just found out in September that my son whose 4 has severe multi nut and seed allergies i think there's definitely some thing in our family were we are prone to these illnesses x
dorat
#72 Posted : Tuesday, December 29, 2009 11:37:10 AM Quote
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Hi Lizzie,

My consultant agrees there are "genetic predispositions" but no actual genetic link has yet been found,
I have hypermobile joints and so has my daughter so I do worry about her getting RA.

Doreen xx
RedDog
#73 Posted : Tuesday, December 29, 2009 11:41:50 AM Quote
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dorat wrote:



I have hypermobile joints.......



I bet you're good on the dance floor Doreen!
A friend is someone who knows all about you but loves you anyway!
dorat
#74 Posted : Tuesday, December 29, 2009 12:21:25 PM Quote
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Of course I am Stewart!

I'm highly sought after for the pole dancing.BigGrin
Blue Star
#75 Posted : Tuesday, December 29, 2009 12:47:32 PM Quote
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LOL LOL LOL
chockers
#76 Posted : Tuesday, December 29, 2009 2:11:33 PM Quote
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Yes i think i started my self off with Stress in 2006
i think it brought it on .
But have i said that .I well belive i had it in 2003 or before as can track it back to silly little things .
But It well reared its ugly head late 2006 and by Jan 07 i went too docs saying have i got R.A (guessed )
Feb 2007 really bad with fevers and never worked since .
I well belive stress was a good factor on bringing it on fast .But the main cause was menopause
may be with out the stress i guess it would had come on slower .As it seemed one day i was working a shift and the next off sick for ever not able to dress my self .
( i have more then R.A maybe why it was fast when it did come on )

christine

My stress was in 2005 someone really upset me and i was ill and had a blood test that showed iummue systym was wonkie 2006 Jan i got a other job when i come to hand in my notice they did not want me to leave and went to lenths to try and get me to stay including following me to my work and the writing too them to share me .( i said too the first boss i would stay on with the agency too help out on my days off )
this would be better for the sick lady i looked after if they did not want me too leave .But no i had madness in the end i left both ha ha as with care work you are never out of work .The first boss really annoyed the 2nd who was a young girl of 26 .Agency useless in sorting first boss out or supporting in what i wanted to do . And then by the Nov i started stiffness .
The chocolate eating housewife ...The washer woman .....naughty lady
Calmwater22
#77 Posted : Tuesday, December 29, 2009 3:55:54 PM Quote
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Hi Chrisie
sorry see stresses that led to you having ra appear or wonky immunity as we call it.

Blue star,my cousin has anksloysing spondlityitis ,my aunt had ra, and lupus.
dad has lupus dle type.
mum osteoarthritis.
gran had ra and suspected lupus died kidney failure.
great gran one side lupus all on my dads side family the immune problems.
apreantly my aunt,grana dn other aunt all had suspected endometrois problem to.
my other cousins all fine.
just me and 1 cousin who affected out 7 cousins.

rheumy pays most attention to me how i am butf amily history a they call it is strong part in what they testing me for.
genetic wise thats my hubby side things.
cmt his dad has it brother has it,mum has bone deformity but not cmt.gran had it also.

so genetic wise we have 1 in2 chance child we have to be born with cmt or not.

we had genetic counselling this summer .
but only cmt was taken into account.
deosnt matter i dont have it.
but saying that child may be fine.
stress was big link to all my fmaily members illnesses starting.
my cousin was very premeature weighed 1 lb inw eight age 11 as started show its self afetr truamatic childhood.

melly
cuddly cats make my world seem so much more fun
barbara-o
#78 Posted : Tuesday, December 29, 2009 5:41:09 PM Quote
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Dear Lizzy,

Thank you for sharing something very personal and what must have been emotionally quite difficult to write. Like Amanda has said, as a mother I can only begin to imagine what you and your family must have gone through, and possibly still do when thinking about your mother.

In my opinion the link between RA and stress is plausible, but off the top of my head do not know of any research in the area. However, I will have a look for you when I get a spare moment and will do a literature review, and will let you know if I find any published research on the subject.

As far as I know, stress has an auto-immune response and triggers our "Flight of Fight" reflex when we are confronted with perceived stressful situations. As I understand stress is linked to the hormones cortisol, adrenaline, noradrenaline, which are located in the adrenal gland and part of the bodies endocrine system. How this might be linked with RA is another question? as we have individual genetic make ups, i.e a possible genetic predisposition to developing a particular disease, and environmental factors/triggers may also play a role. My rheumy believes that researchers will come up with all sorts of links to RA that is of little use to the patients care or treatment. I tend at times to agree, but also disagree with him and want to keep an open mind and opinion on most subjects. I certainly believe that RA maybe triggered by trauma, be it physical or non, following a viral infection or hormonal changes.

I have had a stressful life and do have a stressful job so would not be surprised if my RA was brought on by accumulative stress over the years.

On a different subject, I was also thinking that in order to open up a wider discussion should we start a new post under RA discussions only?

Love,

Barbara
XXXXXX

chockers
#79 Posted : Tuesday, December 29, 2009 11:46:19 PM Quote
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inky07 wrote:
Hi Chrisie
sorry see stresses that led to you having ra appear or wonky immunity as we call it.

Blue star,my cousin has anksloysing spondlityitis ,my aunt had ra, and lupus.
dad has lupus dle type.
mum osteoarthritis.
gran had ra and suspected lupus died kidney failure.
great gran one side lupus all on my dads side family the immune problems.
apreantly my aunt,grana dn other aunt all had suspected endometrois problem to.
my other cousins all fine.
just me and 1 cousin who affected out 7 cousins.

rheumy pays most attention to me how i am butf amily history a they call it is strong part in what they testing me for.
genetic wise thats my hubby side things.
cmt his dad has it brother has it,mum has bone deformity but not cmt.gran had it also.

so genetic wise we have 1 in2 chance child we have to be born with cmt or not.

we had genetic counselling this summer .
but only cmt was taken into account.
deosnt matter i dont have it.
but saying that child may be fine.
stress was big link to all my fmaily members illnesses starting.
my cousin was very premeature weighed 1 lb inw eight age 11 as started show its self afetr truamatic childhood.

melly

Well look at life .I would go for a baby maybe if these things where easy to live with .??It has a 50 % chance .Maybe i would go for it depending on how the illness afects .I would be praying before hand and putting faith in god .Anything can happin to anyone .Could you appopt ?????

christine
The chocolate eating housewife ...The washer woman .....naughty lady
Blue Star
#80 Posted : Tuesday, December 29, 2009 11:58:17 PM Quote
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Yes thats interesting Inky , its my mums side that have all the problems my dads side was fine, as for ttc would you not consider adopting like Christine suggests ?
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